Soluble CD86 protein in serum samples of patients with asthma

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Soluble CD86 protein in serum samples of patients with asthma.

BACKGROUND Previous studies have reported that soluble (s) CD86 is involved in the initiation of the immune response. A study was undertaken to investigate the concentrations of sCD86 in serum samples from patients with bronchial asthma and to determine the cell origin of sCD86. METHODS Serum sCD86 concentrations were measured in 52 asthmatic subjects and 25 non-atopic normal volunteers using...

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Decreased Levels of Soluble Toll-Like Receptor 2 in Patients with Asthma

Background: Recently, reports have indicated a role for the membrane form of Toll-like Receptor 2 (TLR2) in asthma pathogenesis. In this study we examined soluble TLR2 levels in serum and sputum of asthmatic and healthy subjects. Methods: Serum and sputum samples were obtained from 33 asthmatic and 19 healthy subjects. The asthmatics were classified into four groups according to the Global I...

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Soluble CD163 Levels and CD163+CD14+ Monocyte/Macrophage Counts in Patients with Asthma

Background: CD163-expressing macrophages are involved in the inflammatory response in asthma. Objective: To assess sputum and serum soluble CD163 (sCD163) and cytokine levels in patients with asthma. Further discussed was the difference between sCD163 and other classic inflammatory mediators. Methods: Sputum was successfully induced in asthma patients (n=85) and healthy controls (n=21). Interle...

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ژورنال

عنوان ژورنال: Thorax

سال: 2004

ISSN: 0040-6376

DOI: 10.1136/thx.2004.021840